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- The USS Jenolan, while en route to the retirement colony on Norpin V, encounters a Dyson sphere. The Jenolan becomes trapped in the sphere's gravity well and crashes. The only two survivors, Ensign Matt Franklin and passenger Captain Montgomery Scott, unable to wait for a rescue, place themselves in suspended animation by storing their patterns in the pattern buffer of the ship's transporter. (TNG: "Relics")
- 38325.3 - A northern continent on Oby VI is afflicted by a plasma plague. Dr. Susan Nuress, the principal investigator, and her associates are sent by the Federation to find a cure. The initial cure proves ineffective. (TNG: "The Child")