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McCoy might refer to:
- Leonard McCoy, chief surgeon of the USS Enterprise
- Leonard McCoy, chief surgeon of the USS Enterprise in an alternate timeline created by Nero's incursion
- Leonard McCoy, mirror universe counterpart, serving aboard the ISS Enterprise (NCC-1701)
- David McCoy, father of Leonard McCoy
- Joanna McCoy, daughter of Leonard McCoy
- Leonard McCoy's Comparative Alien Physiology, a medical text written by Dr. McCoy
- McCoy, a brand of surfboard
- Production staff and performers
- James L. McCoy, make-up artist for a number of Star Trek films
- Matt McCoy, the actor who portrayed Devinoni Ral