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Sector 001 or Sol Sector was a region of space in the Alpha Quadrant. This was the central sector of the United Federation of Planets in which the Sol system and 40 Eridani A were located. (TNG: "The Best of Both Worlds"; DS9: "Emissary"; VOY: "Endgame"; TNG: "The Wounded", "Night Terrors" dedication plaques)
In 2371, a microscopic singularity passed through Sector 001 and exploded. This created the conditions for an accident that sent Benjamin Sisko, Jadzia Dax and Julian Bashir back in time to the year 2024. (DS9: "Past Tense, Part I")